发酵液中苄胺的纯化工艺研究

Jing Qiu; Jingxin Yin; Jiani Yang; Dongxin Zhao; Hui Zhang; Haijun Gao

doi:10.20075/j.cnki.issn.1003-9384.2025.02.012

发酵液中苄胺的纯化工艺研究

Translated title of the contribution: STUDY ON PURIFICATION TECHNOLOGY OF BENZYLAMINE FROM FERMENTATION BROTH

Jing Qiu, Jingxin Yin, Jiani Yang, Dongxin Zhao, Hui Zhang^*, Haijun Gao^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

This paper uses liquid-liquid extraction and vacuum distillation to separate and purify benzylamine from microbial fermentation liquid. Dichloromethane was selected as the extractant from five organic solvents after Screening experiments. After adjusting the pH to 11 and removing suspended solids by centrifugation, the fermentation liquid was subjected to three rounds of extraction, with extraction rates of 81. 3%, 79. 1%, and 56. 4%, respectively, and a total extraction rate of 98. 3%. The vacuum distillation was carricd out at 30 °C and 0. 07 MPa vacuum, and the recovery rate of benzylamine was 94%. The established extraction-vacuum distillation process can cfficicntly extraction of benzylamine from fermentation liquid, with simple Operation, casy expansion, and high recovery rate.

Translated title of the contribution	STUDY ON PURIFICATION TECHNOLOGY OF BENZYLAMINE FROM FERMENTATION BROTH
Original language	Chinese (Traditional)
Pages (from-to)	52-56
Number of pages	5
Journal	Speciality Petrochemicals
Volume	42
Issue number	2
DOIs	http://doi.org/10.20075/j.cnki.issn.1003-9384.2025.02.012
Publication status	Published - Mar 2025
Externally published	Yes

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10.20075/j.cnki.issn.1003-9384.2025.02.012

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title = "发酵液中苄胺的纯化工艺研究",

abstract = "This paper uses liquid-liquid extraction and vacuum distillation to separate and purify benzylamine from microbial fermentation liquid. Dichloromethane was selected as the extractant from five organic solvents after Screening experiments. After adjusting the pH to 11 and removing suspended solids by centrifugation, the fermentation liquid was subjected to three rounds of extraction, with extraction rates of 81. 3\%, 79. 1\%, and 56. 4\%, respectively, and a total extraction rate of 98. 3\%. The vacuum distillation was carricd out at 30 °C and 0. 07 MPa vacuum, and the recovery rate of benzylamine was 94\%. The established extraction-vacuum distillation process can cfficicntly extraction of benzylamine from fermentation liquid, with simple Operation, casy expansion, and high recovery rate.",

keywords = "benzylamine, dichloromethane, fermentation broth, liquid-liquid extraction, vacuum distillation",

author = "Jing Qiu and Jingxin Yin and Jiani Yang and Dongxin Zhao and Hui Zhang and Haijun Gao",

year = "2025",

month = mar,

doi = "10.20075/j.cnki.issn.1003-9384.2025.02.012",

language = "繁体中文",

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pages = "52--56",

journal = "Speciality Petrochemicals",

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TY - JOUR

T1 - 发酵液中苄胺的纯化工艺研究

AU - Qiu, Jing

AU - Yin, Jingxin

AU - Yang, Jiani

AU - Zhao, Dongxin

AU - Zhang, Hui

AU - Gao, Haijun

PY - 2025/3

Y1 - 2025/3

N2 - This paper uses liquid-liquid extraction and vacuum distillation to separate and purify benzylamine from microbial fermentation liquid. Dichloromethane was selected as the extractant from five organic solvents after Screening experiments. After adjusting the pH to 11 and removing suspended solids by centrifugation, the fermentation liquid was subjected to three rounds of extraction, with extraction rates of 81. 3%, 79. 1%, and 56. 4%, respectively, and a total extraction rate of 98. 3%. The vacuum distillation was carricd out at 30 °C and 0. 07 MPa vacuum, and the recovery rate of benzylamine was 94%. The established extraction-vacuum distillation process can cfficicntly extraction of benzylamine from fermentation liquid, with simple Operation, casy expansion, and high recovery rate.

AB - This paper uses liquid-liquid extraction and vacuum distillation to separate and purify benzylamine from microbial fermentation liquid. Dichloromethane was selected as the extractant from five organic solvents after Screening experiments. After adjusting the pH to 11 and removing suspended solids by centrifugation, the fermentation liquid was subjected to three rounds of extraction, with extraction rates of 81. 3%, 79. 1%, and 56. 4%, respectively, and a total extraction rate of 98. 3%. The vacuum distillation was carricd out at 30 °C and 0. 07 MPa vacuum, and the recovery rate of benzylamine was 94%. The established extraction-vacuum distillation process can cfficicntly extraction of benzylamine from fermentation liquid, with simple Operation, casy expansion, and high recovery rate.

KW - benzylamine

KW - dichloromethane

KW - fermentation broth

KW - liquid-liquid extraction

KW - vacuum distillation

UR - http://www.scopus.com/pages/publications/105003714219

U2 - 10.20075/j.cnki.issn.1003-9384.2025.02.012

DO - 10.20075/j.cnki.issn.1003-9384.2025.02.012

M3 - 文章

AN - SCOPUS:105003714219

SN - 1003-9384

VL - 42

SP - 52

EP - 56

JO - Speciality Petrochemicals

JF - Speciality Petrochemicals

IS - 2

ER -

发酵液中苄胺的纯化工艺研究

Abstract

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