Research output per year
Research output per year
Personal profile
Personal profile
Ni Junjun, male, born in 1988, PhD, Special Researcher/Pre-appointed Associate Professor
Email: nijunjun@dijiaba.com
Office Address: 609 Building 5, Beijing Institute of Technology
Ni Junjun, male, born in 1988, PhD, Special Researcher/Pre-appointed Associate Professor
Email: nijunjun@dijiaba.com
Office Address: 609 Building 5, Beijing Institute of Technology
Ni Junjun, male, born in 1988, PhD, Special Researcher/Pre-appointed Associate Professor
Email: nijunjun@dijiaba.com
Office Address: 609 Building 5, Beijing Institute of Technology
Research Interests
1. Molecular mechanisms of aging and neurodegenerative diseases;
2. Study on pathological function of cathepsin family;
3. Study on the immune characteristics of microglia under physiological and pathological conditions;
4. Study on the relationship and mechanism between oral diseases and brain cognitive function.
1. Molecular mechanisms of aging and neurodegenerative diseases;
2. Study on pathological function of cathepsin family;
3. Study on the immune characteristics of microglia under physiological and pathological conditions;
4. Study on the relationship and mechanism between oral diseases and brain cognitive function.
Education
2012.10-2016.3 Kyushu University, School of Dentistry, Geriatrics and Pharmacology, PhD,
2010.9-2012.7 Master of Neurobiology, School of Life Sciences, Beijing Institute of Technology,
2006.9-2010.7 Biotechnology, College of Medicine, Qingdao University
Professional Experience
2019.11-present, Beijing Institute of Technology, School of Life Sciences, Special Researcher
2016.3-2019.10 Assistant Professor of Gerontology and Pharmacology, Kyushu University, School of Dentistry
2019.11-present, Beijing Institute of Technology, School of Life Sciences, Special Researcher
2016.3-2019.10 Assistant Professor of Gerontology and Pharmacology, Kyushu University, School of Dentistry
Research Achievement
1. National Natural Science Foundation of China, Surface Project, 32070954, Microglia and Neuronal tissue proteinase B involved in the pathogenesis of Alzheimer's Disease, 2021-2024-12, 580,000 yuan, ongoing research, Host.
2. Beijing Municipal Science and Technology Commission, Surface Project, 7212066, The role and mechanism of cathepsin B in regulating neuronal function in Alzheimer's Disease, 2021-2023-12, 200,000 yuan, Ongoing research, Host.
3. Beijing Institute of Technology, Science and Technology Innovation Program, 2020CX04166, The role and mechanism of cathepsin E in regulating microglia function in Alzheimer's Disease, 2020-1 to 2022-12, 600,000 yuan, Ongoing research, Host.
4. Japan Academic Promotion Association, Young Scholars Research Fund, JP17K17093, The role of cathepsins in Aβ degradation in Alzheimer's -like disease, 2017-4 to 2019-3, 4.16 million yen (274,000 yuan), closed, host.
5. Japan Association for The Promotion of Academia, Challenging Budding Fund, JP18K19650, The effects of gingipain on the pathogenesis of Alzheimer's disease, 2018-6 to 2021-3, 6.37 million yen (390,000 yuan), completed, participate.
6. National Natural Science Foundation of China, Surface Project, 81171206, Study on the regulation of β-secretase (BACE1) by Premature aging Factor and the pathogenesis of Alzheimer's Disease, 2012-01 to 2015-12,600 million yuan, completed, participated.
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- 6 Similar Profiles
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Cathepsin B deficiency disrupts cortical development via PEG3, leading to depression-like behavior
Xie, Z., Yang, Q., Lan, F., Kong, W., Zhao, S., Sun, J., Yan, Y., Quan, Z., Bai, Z., Qing, H., Mao, J. & Ni, J., Dec 2025, In: Communications Biology. 8, 1, 1097.Research output: Contribution to journal › Article › peer-review
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Cathepsin B Modulates Alzheimer's Disease Pathology Through SAPK/JNK Signals Following Administration of Porphyromonas gingivalis-Derived Outer Membrane Vesicles
Jiang, M., Ge, Z., Yin, S., Liu, Y., Gao, H., Lu, L., Wang, H., Li, C., Ni, J., Pan, Y. & Lin, L., Mar 2025, In: Journal of Clinical Periodontology. 52, 3, p. 434-456 23 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Cathepsin B modulates microglial migration and phagocytosis of amyloid β in Alzheimer’s disease through PI3K-Akt signaling
Jiang, M., Zhao, D., Zhou, Y., Kong, W., Xie, Z., Xiong, Y., Li, Y., Zhao, S., Kou, X., Zhang, S., Meng, R., Pan, Y., Wu, Z., Nakanishi, H., Zhao, J., Li, H., Quan, Z., Lin, L., Qing, H. & Ni, J., Mar 2025, In: Neuropsychopharmacology. 50, 4, p. 640-650 11 p., 255.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Deciphering T Cell Dynamics in Alzheimer's Disease Pathogenesis: Insights and Implications
Yang, Q., Qiu, Y., Ni, J., Li, H. & Qing, H., 2025, (Accepted/In press) In: Current Neuropharmacology.Research output: Contribution to journal › Review article › peer-review
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Extracellular vesicle-packed microRNAs profiling in Alzheimer's disease: The molecular intermediary between pathology and diagnosis
Arif, S., Qazi, T. J., Quan, Z., Ni, J., Li, Z., Qiu, Y. & Qing, H., Feb 2025, In: Ageing Research Reviews. 104, 102614.Research output: Contribution to journal › Review article › peer-review
3 Citations (Scopus)